The Effect Of Cardiovascular Disease On The

DOI: This is due to traditional risk factors and the effects of chronic inflammation.

Higher Risk Of Surgery As A Patient For Elective Total Hip Replacement Surgery

Methods: We searched Medline, Embase, Cochrane database, database of abstracts of reviews of effects, health technology assessment and Science Citation Index from to Two reviewers independently assessed each title and abstract for relevance and quality. Results: A total of abstracts were identified, of which 18 fulfilled the inclusion criteria.

Two studies assessed the relationship between MTX use and CVD mortality, one demonstrated a significant reduction in CVD mortality and the second a trend towards reduction. Five studies considered all-cause CVD morbidity.

Four demonstrated a significant reduction in CVD morbidity and the fifth a trend towards reduction. Four studies considered myocardial infarction, one demonstrated a decreased risk and three a trend towards decreased risk with MTX use.

This suggests that reducing the inflammation in RA using MTX not only improves disease-specific outcomes but may also reduce collateral damage such as atherosclerosis. Publication types.]