Long-acting beta agonist
Objective: To assess the relationship between patterns of use of therapy and asthma exacerbations AEx. Methods: Patients with asthma years were enrolled in France and the United Kingdom. Prescribing data, computer-assisted telephone interviews CATIsand text messages assessed medication use and AEx over a maximum period of 24 months.
Generalized linear mixed models provided AEx risks associated with therapy. Results: Among the patients median age: Regular ie, daily or almost daily SABA use was observed for Altogether, patients The OR was 2.
Compared with non-users, the risk of exacerbation increased moderately under regular use of single LABAs, whereas it doubled, significantly, in regular SABA users, likely in relationship with poor overall asthma control.]
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Planned treatment used for analysis. Subjects can have one or more events, but only the first event was counted for analysis. A single, blinded, independent adjudication committee determined whether events were asthma related. There were no asthma-related deaths or intubations. Serious acute respiratory events, including fatalities, have been reported when salmeterol, a component of this product, has been initiated in patients with significantly worsening or acutely deteriorating asthma. In most cases, these have occurred in patients with severe asthma e. long-acting beta agonist.For: Long-acting beta agonist
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