Common Hydrogen Bonds

Common hydrogen bonds

The concept of supramolecular chemistry can be applied to the design of new pharmaceutical materials affording new compositions of matter with desirable composition, structure and properties.

By identifying reliable connectors through molecular recognition or self-assembly, one can build predictable architectures. The study of supramolecular synthesis was accomplished using known pharmaceutical molecules such as Nifedipine calcium channel blocker used for cardiovascular diseases and Phenytoin used as an anticonvulsant drug and model compounds containing synthons common in pharmaceutical common hydrogen bonds Crown ethers and Trimesic acid with ether linkages and carboxylic acid dimers, respectively with complementary molecular additives.

The co-crystals formed were characterized by various techniques IR, m. These crystalline assemblies could afford improved solubility, dissolution rate, stability and bioavailability.

Graduate Theses and Dissertations.]

Common hydrogen bonds - message simply

Structure[ edit ] The structure of hydrogen disulfide is similar to that of hydrogen peroxide , with C2 point group symmetry. Both molecules are distinctly nonplanar. The dihedral angle is Fractional distillation of this oil gives hydrogen disulfide separate from any other polysulfides mostly trisulfide. Trost and Hornberger [6] have calculated that while an isolated DSSD molecule would spontaneously oscillate between left and right chiral forms with a period of 5. common hydrogen bonds.