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How to kiss your man passionately in sp

Jul 28,  · The first pass effect is a phenomenon in which a drug gets metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action or the systemic circulation. The first pass effect is often associated with the liver, as this is a major site of drug metabolism. However, the first pass effect can also Author: Timothy F. Herman, Cynthia Santos. Feb 29,  · first-pass effect is a process in which a drug administered by mouth is absorbed from the gastrointestinal tract and transported via the portal vein to the liver, where it is metabolized. As a result, in cases of some drugs, only a small proportion of the active drug reaches the systemic circulation and its intended target tissue. The first-pass effect (or first-pass metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the entire body.. After a drug is swallowed, it is absorbed by the digestive system and enters the hepatic portal Modernalternativemama is carried through the portal vein into the liver before it reaches the rest of the body. Read more

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