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Carbohydrate Fat Protein. % of calories Primarily corn syrup solids Corn oil Soybean oil Casein Soy protein isolates Most formulas do NOT contain lactose. Standard/Polymeric Formulations. kcal/ml PRO CHO FAT PRO source n6:n3 fiber (g/L) osmlality Nutren 1 16% 51% 33% caseinate (14) Jul 28,  · The first pass effect is often associated with the liver, as this is a major site of drug metabolism. However, the first pass effect can also occur in the lungs, vasculature, gastrointestinal tract, and other metabolically active tissues in the body. This effect can become augmented by various factors such as plasma protein concentrations Author: Timothy F. Herman, Cynthia Santos. Jun 12,  · How do you calculate bioavailability of a drug? The absolute bioavailability is the dose-corrected area under curve (AUC) non-intravenous divided by AUC intravenous. The formula for calculating the absolute bioavailability, F, of a drug administered orally (po) is given below (where D is dose administered). Click to see full answer. Read more