Explain first pass metabolism chart answers
by Mike_B
First-pass elimination takes place when a drug is metabolised between its site of administration and the site of sampling for measurement of drug concentration. Clinically, first-pass metabolism is important when the fraction of the dose administered that escapes metabolism is small and Modernalternativemama: Susan M. Pond, Susan M. Pond, Thomas N. Tozer, Thomas N. Tozer. Jul 28, · The first pass effect is often associated with the liver, as this is a major site of drug metabolism. However, the first pass effect can also occur in the lungs, vasculature, gastrointestinal tract, and other metabolically active tissues in the body. This effect can become augmented by various factors such as plasma protein concentrations Author: Timothy F. Herman, Cynthia Santos. Jan 04, · The First Pass Effect. When you take a medication by mouth, it doesn't just magically get into your body and start doing its thing. It actually has to go through a whole host of organs and a big. Read more